Following on from my previous quote from Cosmos, here is another quote. This one is talking about the paradox of the complexity and simplicity of a cell:
If we plunged through a pore into the nucleus of the cell, we would find something that resembles an explosion in a spaghetti factory — a disorderly multitude of coils and strands, which are the two kinds of nucleic acids: DNA, which knows what to do, and RNA, which conveys the instructions issued by DNA to the rest of the cell. These are the best that four billion years of evolution could produce, containing the full complement of information on how to make a cell, a tree or a human work. The amount of information in human DNA, if written out in ordinary language, would occupy a hundred thick volumes. What is more, the DNA molecules know how to make, with only very rare exceptions, identical copies of themselves. They know extraordinarily much.
Yet again, the final sentence strikes me as a wonderful turn of phrase, particularly as I read everything Carl wrote with the memory of his voice and its peculiar tempo playing in my head.
The Human Genome Project was only half-way through mapping the human DNA when Carl died in 1996. The Project ran from 1990-2003 and, just as we once did with hieroglyphics, we are still only just tapping the surface in deciphering what it means nearly ten years later (also see the extensive Wikipedia entry). Since this initial, mammoth breakthrough, many more donor genomes have been sequenced — it seems to be a growing industry.
And as for Carl’s estimate of the size it would take in print form, the original genome has subsequently been printed into 119 bound volumes, containing all of the three billion base pairs. Though I imagine it would make rubbish bedtime reading…
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I’ve recently begun reading Cosmos by Carl Sagan (Amazon|Amazon UK), which is well overdue since the accompanying TV series has been my favourite piece of television since I was in primary school.
While reading Chapter 2, “One Voice in the Cosmic Fugue,” where he’s talking about evolution using his work with Nobel laureate H.J. Muller (discoverer of X-ray mutagenesis) and Drosophila melanogaster fruit flies as an example, a paragraph just jumps out at you:
The secrets of evolution are death and time — the deaths of enormous numbers of lifeforms that were imperfectly adapted to the environment; and time for a long succession of small mutations that were by accident adaptive, time for the slow accumulation of patterns of favorable mutations. Part of the resistance to Darwin and Wallace derives from our difficulty in imagining the passage of the millennia, much less the aeons. What does seventy million years mean to beings who live only one-millionth as long? We are like butterflies who flutter for a day and think it is forever.
What a magnificent turn of phrase. It sums up what we know of artificial and natural selection, underlines the breakthrough of its realisation, and wraps it into a beautiful philosophical illustration.
Knowing the TV series as I do, I’m looking forward to many more stand-out pieces such as this during my journey through the Cosmos, as it were. If you’re good, I may even share them with you…
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A while ago I covered Pascal’s Wager, the logical fallacy used by some religious people to ‘reason’ non-believers into believing ‘just in case’ their particular god story is true. And then along comes a single image to cover it simply and succinctly:

When you then consider the likelihood that this is the only life we get — that there’s nothing once we pop our clogs — all of that suffering, brutality and ignorance becomes tragic.
Of course if there is a god of some kind, then he/she/it/them will appreciate the person who used the brains they were given, rather than hitching their horse to the wagon they were born next to.
Hat tip: LOLgod
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